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Haribabu, Y.
- Bilayer Floating Tablets: An Updated Review
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Authors
Affiliations
1 Research Scholar, Grace College of Pharmacy, Palakkad, Kerala – 678004., IN
2 Associate Professor, Department of Pharmaceutics, Grace College of Pharmacy, Palakkad, Kerala – 678004., IN
3 Principal, Grace College of Pharmacy, Palakkad, Kerala – 678004, IN
1 Research Scholar, Grace College of Pharmacy, Palakkad, Kerala – 678004., IN
2 Associate Professor, Department of Pharmaceutics, Grace College of Pharmacy, Palakkad, Kerala – 678004., IN
3 Principal, Grace College of Pharmacy, Palakkad, Kerala – 678004, IN
Source
Research Journal of Pharmacy and Technology, Vol 15, No 3 (2022), Pagination: 1337-1342Abstract
Various technologies for developing the rate controlled oral drug delivery system were introduced to overcome various physiological problems and to increase the bioavailability of various drugs. Recently bilayer tablets were introduced to attain the combination of different drugs in a single dosage form to prevent incompatibilities, achieve more patient compliance and therapeutic efficiency. Bilayer tablets are the tablets, which consist of two layers in which one layer is designed for sustained release and another layer for immediate release. In bilayer-floating tablet the sustained release is obtained by floating mechanism in which the drug is being made gastro-buoyant by the release of carbondioxide from the ingredients incorporated in it. It is also adopted for improving drug solubility. This review is an attempt to illustrate the major concepts of bilayer-floating tablets.Keywords
Bilayer tablets, Gastric buoyant, Rate controlled system, Immediate release layer.
References
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- A Review on Pulsatile Drug Delivery System: Drug Scheduling Based on Biological Rhythm
Abstract Views :98 |
PDF Views:0
Authors
Affiliations
1 Research Scholar, Grace College of pharmacy, Palakkad, Kerala-678004,, IN
2 Professor, Department of Pharmaceutics, Grace College of Pharmacy, Palakkad, Kerala-678004,, IN
3 Principal, Grace College of Pharmacy, Palakkad, Kerala-678004,, IN
1 Research Scholar, Grace College of pharmacy, Palakkad, Kerala-678004,, IN
2 Professor, Department of Pharmaceutics, Grace College of Pharmacy, Palakkad, Kerala-678004,, IN
3 Principal, Grace College of Pharmacy, Palakkad, Kerala-678004,, IN
Source
Research Journal of Pharmacy and Technology, Vol 15, No 3 (2022), Pagination: 1359-1364Abstract
Advancement in chronopharmacology and the necessity of an appropriate technology for time specific and site specific drug delivery has led to the development of novel type of drug delivery systems as “chronotropic or Pulsatile drug delivery systems”. Rationale for designing pulsatile delivery systems is to release the drug at desired time, which results in improved therapeutic efficacy and patient-outcome. These systems are meant for treatment of those diseases that are caused due to circadian changes in body like asthma, peptic ulcer, cardiovascular diseases, arthritis and when zero order drug release is not desired. These pulsatile delivery systems a releases the drug within a short period of time, immediately after a predetermined lag time. The present article focuses on diseases requiring chronotropic systems and their chronological behaviour, various approaches, recent technologies for chronotherapy and currently available marketed formulations.Keywords
Chronotherapy, Circadian rhythm, Pulsatile drug delivery system, Time controlled chronotropic systems, Stimuli induced pulsatile drug delivery systems.References
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